Non-steroidal analgesics and anti-inflammatory agents.

Peptic ulcer and non-steroidal anti-inflammatory agents.

Aspirin is generally regarded as a cause of gastric ulcer but the role of non-steroidal anti-inflammatory agents and paracetamol in the aetiology of peptic ulcer is unclear. To investigate this we conducted a case control study of 180 matched pairs of peptic ulcer patients and controls obtained from surgical and dermatology outpatient clinics. There were 95 gastric ulcer and 85 duodenal ulcer p...

Non-steroidal anti-inflammatory agents and the gastrointestinal tract.

The chemistry of non-steroidal anti-inflammatory agents.

It is not possible to discuss immediately the chemistry of, and the therapeutic response to, anti-inflammatory agents which do not possess the steroidal skeleton without properly defining the terms. It is even more fundamental, but entirely in order, to make some introductory remarks concerning those small molecules, normally dubbed 'drugs', which are designed to combat diseases of major import...

Non-steroidal anti-inflammatory drugs.

The association between pain intensity and the prescription of analgesics and non-steroidal anti-inflammatory drugs

BACKGROUND It is not known whether general practitioners (GPs) prescribe analgesic medication according to intensity of pain or a hierarchical prescribing regimen. AIMS The aim of this study was to assess the association of strength of pain-relief medication prescribed by the GP with the strength of previous prescription and pain level. METHODS The PROG-RES study collected data on pain inte...